NF-κΒ activator 1

CAS No. 2387524-59-4

NF-κΒ activator 1( —— )

Catalog No. M35172 CAS No. 2387524-59-4

NF-κΒ activator 1 can activate the nf-kappa Β gene activator, EC50 of 0.9 microns.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 132 Get Quote
5MG 202 Get Quote
10MG 330 Get Quote
25MG 542 Get Quote
50MG 775 Get Quote
100MG 1044 Get Quote
500MG 2097 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    NF-κΒ activator 1
  • Note
    Research use only, not for human use.
  • Brief Description
    NF-κΒ activator 1 can activate the nf-kappa Β gene activator, EC50 of 0.9 microns.
  • Description
    NF-κΒ activator 1 is a potent NF-κΒ activator with an EC50 of 0.9 μM. NF-κΒ activator 1 induces superoxide dismutase (SOD)2 mRNA expression.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    NF-κB
  • Recptor
    NF-κB
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2387524-59-4
  • Formula Weight
    314.33
  • Molecular Formula
    C16H11FN2O2S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (318.14 mM; Ultrasonic )
  • SMILES
    OC(=O)c1cccc(c1)-c1csc(Nc2ccccc2F)n1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Mathew B, et al. Structure-activity relationship (SAR) studies of N-(3-methylpyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine (SRI-22819) as NF-?B activators for the treatment of ALS [published online ahead of print, 2020 Oct 22]. Eur J Med Chem. 2020;112952.?
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