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Home - Products - Apoptosis - NF-κB - NF-κΒ activator 1

NF-κΒ activator 1

CAS No. 2387524-59-4

NF-κΒ activator 1( —— )

Catalog No. M35172 CAS No. 2387524-59-4

NF-κΒ activator 1 can activate the nf-kappa Β gene activator, EC50 of 0.9 microns.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    NF-κΒ activator 1
  • Note
    Research use only, not for human use.
  • Brief Description
    NF-κΒ activator 1 can activate the nf-kappa Β gene activator, EC50 of 0.9 microns.
  • Description
    NF-κΒ activator 1 is a potent NF-κΒ activator with an EC50 of 0.9 μM. NF-κΒ activator 1 induces superoxide dismutase (SOD)2 mRNA expression.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    NF-κB
  • Recptor
    NF-κB
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2387524-59-4
  • Formula Weight
    314.33
  • Molecular Formula
    C16H11FN2O2S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (318.14 mM; Ultrasonic )
  • SMILES
    OC(=O)c1cccc(c1)-c1csc(Nc2ccccc2F)n1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Mathew B, et al. Structure-activity relationship (SAR) studies of N-(3-methylpyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine (SRI-22819) as NF-?B activators for the treatment of ALS [published online ahead of print, 2020 Oct 22]. Eur J Med Chem. 2020;112952.?
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